Limitless combines three synergistic compounds that target cellular energy, mitochondrial function, and metabolic regulation: NAD* (Nicotinamide Adenine Dinucleotide): A critical coenzyme present in all living cells. It exists in oxidized (NAD*) and reduced (NADH) forms. MOTS-C: A 16-amino-acid mitochondrial-derived peptide (MDP). Sequence: MRWQEMGYIFYPRKLR. 5-Amino-1MQ: A small-molecule quinolinium derivative (5-amino-1-methylquinolinium). Mechanism of Action NAD* serves as a substrate for sirtuins (SIRT1-7), PARPS, and CD38, regulating DNA repair, mitochondrial biogenesis, circadian rhythm, inflammation, and cellular senescence. Supplementation elevates NAD* levels, restoring sirtuin activity, enhancing mitochondrial efficiency, and supporting energy metabolism. MOTS-C acts as a retrograde mitochondrial signal. It activates AMPK, promotes PGC-1a expression, increases fatty acid oxidation, improves insulin sensitivity, enhances metabolic flexibility, and protects against age- and diet-induced metabolic dysfunction. 5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT). By blocking NNMT, it reduces 1- methylnicotinamide production, preserves nicotinamide for NAD* synthesis, increases intracellular NAD*, shifts metabolism toward oxidative pathways, reduces fat storage, and enhances mitochondrial function and energy expenditure. The triple combination works synergistically to elevate NAD* pools, optimize mitochondrial performance, improve metabolic efficiency, reduce adipose accumulation, and support cellular resilience and longevity pathways. Indications & Usage Limitless is used to support cellular energy, metabolic health, and longevity processes. It is indicated for: Enhancement of mitochondrial function and energy production Promotion of fat oxidation and healthy body composition Support for metabolic flexibility and insulin sensitivity Assistance in cellular repair, resilience, and anti-aging metabolic pathways Contraindications & Warnings Do not use if you have: Known hypersensitivity to NAD*, MOTS-C, 5-Amino-1MQ, or any excipient Active malignancy or history of cancer Severe uncontrolled diabetes mellitus or insulin resistance syndromes Severe hepatic or renal impairment Pregnancy or breastfeeding Age under 18 years
